MSIP is designed for Mass Specrometry based Isotopomer Parsing. To boost comprehensive metabolic flux analysis ( MFA ) based on Isotopomer.
Access our demo dataset of project Three one carbon labeled glucose for a practical biological application.
We also designed a visual tool MFNA for isotopomers understanding, see Metabolic Flux Network Analysis for more detail, and Metabolic Flux Network from glucose to GSH for demo
What is isotopomers
• Isotopologues are molecules differing only in their isotopic composition. Two isotopologues are the same chemical species, but with at least one atom containing a different number of neutrons. The term isotopologue is derived from ‘isotope’ and ‘homologue’.
• Isotopomers are defined as molecules having the same number of each isotopic atom, but differing in their positions. The term isotopomer is a portmanteau of ‘isotope’ and ‘isomer’.
Why isotopomers
In the complicated biological metabolic network, some of metabolic process could not be reflected in the isotopologues, especailly when mulitple reactions generating the same isotopologue but distinct isotopomers.
